Structure of PDB 6u74 Chain A

Receptor sequence
>6u74A (length=128) Species: 9606 (Homo sapiens) [Search protein sequence]
LGSSTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVD
AVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYI
YNKPGDDIVLMAEALEKLFLQKINELPT
3D structure
PDB6u74 Cyclic peptides can engage a single binding pocket through highly divergent modes.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F83 V87 L94 I100 I138 Y139 N140 K141 D144 D145 F45 V49 L56 I62 I100 Y101 N102 K103 D106 D107
External links
PDB RCSB:6u74, PDBe:6u74, PDBj:6u74
PDBsum6u74
PubMed33046654
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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