Structure of PDB 6u71 Chain A

Receptor sequence
>6u71A (length=110) Species: 9606 (Homo sapiens) [Search protein sequence]
SSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMD
LSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDV
FEFRYAKMPD
3D structure
PDB6u71 Cyclic peptides can engage a single binding pocket through highly divergent modes.
ChainA
Resolution1.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A W370 P371 V376 L381 N429 H433 D434 V435 W25 P26 V31 L36 N84 H88 D89 V90
External links
PDB RCSB:6u71, PDBe:6u71, PDBj:6u71
PDBsum6u71
PubMed33046654
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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