Structure of PDB 6u6l Chain A

Receptor sequence
>6u6lA (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
SKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHP
MDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQ
DVFEMRFAKMPD
3D structure
PDB6u6l Cyclic peptides can engage a single binding pocket through highly divergent modes.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A F376 L387 N433 E438 F29 L40 N86 E91
External links
PDB RCSB:6u6l, PDBe:6u6l, PDBj:6u6l
PDBsum6u6l
PubMed33046654
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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