Structure of PDB 6u4a Chain A

Receptor sequence
>6u4aA (length=120) Species: 9606 (Homo sapiens) [Search protein sequence]
NPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKII
KNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQ
ALEKIFLQKVAQMPQEEVEL
3D structure
PDB6u4a Cyclic peptides can engage a single binding pocket through highly divergent modes.
ChainA
Resolution1.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A W57 V63 L68 N116 D120 D121 I122 M125 W30 V36 L41 N89 D93 D94 I95 M98
External links
PDB RCSB:6u4a, PDBe:6u4a, PDBj:6u4a
PDBsum6u4a
PubMed33046654
UniProtQ15059|BRD3_HUMAN Bromodomain-containing protein 3 (Gene Name=BRD3)

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