Structure of PDB 6u3m Chain A

Receptor sequence
>6u3mA (length=181) Species: 9606 (Homo sapiens) [Search protein sequence]
IVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGRKETVWSLPVLR
QFRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLG
QPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISY
LTLLPSAEESYDCKVEHWGLDKPLLKHWEPE
3D structure
PDB6u3m T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y9 H24 F51 F54 F58 N62 V65 N69 S72 L73 R76 Y9 H25 F52 F54 F58 N62 V65 N69 S72 L73 R76
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6u3m, PDBe:6u3m, PDBj:6u3m
PDBsum6u3m
PubMed31873306
UniProtP01909|DQA1_HUMAN HLA class II histocompatibility antigen, DQ alpha 1 chain (Gene Name=HLA-DQA1)

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