Structure of PDB 6tzm Chain A

Receptor sequence
>6tzmA (length=211) Species: 237561 (Candida albicans SC5314) [Search protein sequence]
STTTKYIFVPIATIGCGKTTVFNTLNNLFPQWTHIQNDNISKKAKLKICD
LTLLALEDDDQSVVLFDRNNSASRERRQIFTTIDQKRDEHLDDTVDLKYI
AINFIPEDLSEEELWDITYNRVIQLDENLVESVMKGFIQRYQPINTSRSP
DDQFDHVIHLKLSKDENSLKSSLENVRIIIDDLVQNFPDLIKEKPADELI
NECFQKALDYK
3D structure
PDB6tzm Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor.
ChainA
Resolution1.714 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.5.1.3: RNA ligase (ATP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A G422 G424 K425 T426 T427 R528 D583 K588 S589 S590 G15 G17 K18 T19 T20 R121 D165 K170 S171 S172
Gene Ontology
Molecular Function
GO:0003972 RNA ligase (ATP) activity
GO:0005524 ATP binding
Biological Process
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation

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Molecular Function
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Biological Process
External links
PDB RCSB:6tzm, PDBe:6tzm, PDBj:6tzm
PDBsum6tzm
PubMed31722405
UniProtP43075|TRNL_CANAL tRNA ligase (Gene Name=LIG1)

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