Structure of PDB 6twn Chain A

Receptor sequence
>6twnA (length=306) Species: 10090 (Mus musculus) [Search protein sequence]
PFTKHGQKECDNALRQLETVRELLENPVQPINDMSYFGCLDSVMENSKVL
GEAMTGISQNAKNGNLPEFGDAIATASKALCGFTEAAAQAAYLVGVSDPN
SQAGQQGLVEPTQFARANQAIQMACQSLGEPGCTQAQVLSAATIVAKHTS
ALCNSCRLASARTANPTAKRQFVQSAKEVANSTANLVKTIKALDGDFTEE
NRAQCRAATAPLLEAVDNLSAFASNPEFSSVPAQISPEGRAAMEPIVISA
KTMLESAGGLIQTARALAVNPRDPPRWSVLAGHSRTVSDSIKKLITSMRD
KAPGQL
3D structure
PDB6twn Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1.
ChainA
Resolution2.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A L1492 A1495 T1496 A1499 K1500 S1503 K1544 L139 A142 T143 A146 K147 S150 K191
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6twn, PDBe:6twn, PDBj:6twn
PDBsum6twn
PubMed34118235
UniProtP26039|TLN1_MOUSE Talin-1 (Gene Name=Tln1)

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