Structure of PDB 6tle Chain A

Receptor sequence
>6tleA (length=338) Species: 9606 (Homo sapiens) [Search protein sequence]
KNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTY
TFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTME
GERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNE
ELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEK
GAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDL
AGSERAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGG
RTRTSIIATISPASLNLKETLSTLEYAHRAKNILNKPE
3D structure
PDB6tle Human Eg5 motor domain mutant E344K
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A R26 P27 T107 G108 G110 K111 T112 F113 E118 R10 P11 T91 G92 G94 K95 T96 F97 E102
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:6tle, PDBe:6tle, PDBj:6tle
PDBsum6tle
PubMed
UniProtP52732|KIF11_HUMAN Kinesin-like protein KIF11 (Gene Name=KIF11)

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