Structure of PDB 6tbz Chain A

Receptor sequence
>6tbzA (length=127) Species: 9606 (Homo sapiens) [Search protein sequence]
SPAVKRLLGWKQGEQNGQEEKWAEKAVDALVKKLKKKKGAMEELEKALSS
PGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLD
ICEFPFGSKQKEVCINPYHYKRVESPV
3D structure
PDB6tbz Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes.
ChainA
Resolution1.782 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A L72 Q77 S79 H80 L64 Q69 S71 H72
BS02 dna A K40 R75 H101 K32 R67 H93
BS03 ZN A C65 C110 C122 H127 C57 C102 C114 H119
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005667 transcription regulator complex

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Biological Process
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Cellular Component
External links
PDB RCSB:6tbz, PDBe:6tbz, PDBj:6tbz
PDBsum6tbz
PubMed33510867
UniProtQ56I99|SMAD5_CHICK Mothers against decapentaplegic homolog 5 (Gene Name=SMAD5)

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