Structure of PDB 6t93 Chain A

Receptor sequence
>6t93A (length=96) Species: 9606 (Homo sapiens) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGE
3D structure
PDB6t93 Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
ChainA
Resolution3.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R43 T46 R73 R84 F85 Q86 R117 V118 T119 R5 T8 R35 R46 F47 Q48 R79 V80 T81
BS02 dna A R41 Y42 P44 G45 R64 K65 L66 R3 Y4 P6 G7 R26 K27 L28
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0045296 cadherin binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0010467 gene expression
GO:0032200 telomere organization
GO:0040029 epigenetic regulation of gene expression
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0070062 extracellular exosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6t93, PDBe:6t93, PDBj:6t93
PDBsum6t93
PubMed32327602
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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