Structure of PDB 6t8h Chain A

Receptor sequence
>6t8hA (length=420) Species: 272844 (Pyrococcus abyssi GE5) [Search protein sequence]
NYEVKFDVRQVKLRPPKVGKEGEIIVEAYASLFKSRLSKLKRILRENPEI
SNVVDIGKLNYVSGDEEVTIIGLVNSKRETNRGLIFEVEDKTGIVKVFLP
KDSEDYREAFKVLPDAVVAFKGFYSKKGIFFANKFYLPDVPLYRKQKPPL
EEKVYAILISDIHVGSREFCEKAFLKFLEWLNGHVESKEEEEIVSRVKYL
IIAGDVVDGIGIYPGQYSDLVIPDIFDQYEALANLLANVPEHITMFIGPG
NADAARPAIPQPEFYKEYAKPIYKLKNAIIISNPAVIRLHGRDFLIAHGR
GIEDVVSFVPGLTHHKPGLPMVELLKMRHLAPTFGGKVPIAPDPEDLLVI
EEVPDLVQMGHVHVYDAVVYRGVQLVNSATWQAQTEFQKMVNIVPTPAKV
PVVDVESARVVKVLDFSGWC
3D structure
PDB6t8h Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.
ChainA
Resolution3.77 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.1: exodeoxyribonuclease I.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A D360 H362 D404 H560 H562 D161 H163 D205 H361 H363
BS02 ZN A D404 N450 H497 H560 D205 N251 H298 H361
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0008310 single-stranded DNA 3'-5' DNA exonuclease activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006308 DNA catabolic process
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0042575 DNA polymerase complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6t8h, PDBe:6t8h, PDBj:6t8h
PDBsum6t8h
PubMed32221299
UniProtQ9V2F3|DP2S_PYRAB DNA polymerase II small subunit (Gene Name=polB)

[Back to BioLiP]