Structure of PDB 6t79 Chain A

Receptor sequence
>6t79A (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVGLFEDTNLAAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB6t79 Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y41 R42 T45 R72 R83 F84 Q85 R116 V117 T118 M120 Y5 R6 T9 R36 R47 F48 Q49 R80 V81 T82 M84
BS02 dna A R40 Y41 G44 V46 A47 K56 R63 L65 R69 R83 R4 Y5 G8 V10 A11 K20 R27 L29 R33 R47
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6t79, PDBe:6t79, PDBj:6t79
PDBsum6t79
PubMed32350470
UniProtQ71DI3|H32_HUMAN Histone H3.2 (Gene Name=H3C15)

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