Structure of PDB 6t48 Chain A

Receptor sequence
>6t48A (length=271) Species: 1330520 (Enterovirus F) [Search protein sequence]
GQVIKSAVRSTVENTVQSTHSITTEATPALQAAETGATSNASDESMIETR
NVVNTHGVAETSLEAFYGRAGLVAMFSTDGGIYRWYINFGEYVQLRAKLE
LLTYARFDMEFTIVAQVVNAQSKVQDFNVDYQVMFVPPGASVPENQDSYQ
WQSSCNPSVISNTGLPPARVSVPFMSSANAYSFSYDGYTQFGDTSGSSYG
IVPSNYLGMLVVRTCEDLDGTRLRVRVYAKPKHVKGWIPRSPRMTPYKSR
YTGVYTDTTKFCANRARITTA
3D structure
PDB6t48 Glutathione facilitates enterovirus assembly by binding at a druggable pocket.
ChainA
Resolution2.17 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CYS A M247 T248 P249 M244 T245 P246
BS02 GSH A M78 R229 M75 R226
BS03 GLY A M247 F264 M244 F261
External links