Structure of PDB 6t22 Chain A

Receptor sequence
>6t22A (length=145) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
EFMHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYII
ERLVDSGVSQVVVYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRL
KMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRG
3D structure
PDB6t22 Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
ChainA
Resolution2.21 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.21.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A S30 W31 G32 P33 S65 S66 S108 R109 K113 G118 N119 T121 K122 S32 W33 G34 P35 S67 S68 S110 R111 K115 G120 N121 T123 K124
BS02 dna A W31 P33 G34 R97 R120 W33 P35 G36 R99 R122
External links
PDB RCSB:6t22, PDBe:6t22, PDBj:6t22
PDBsum6t22
PubMed31724709
UniProtP24200|MCRA_ECOLI Type IV methyl-directed restriction enzyme EcoKMcrA (Gene Name=mcrA)

[Back to BioLiP]