Structure of PDB 6t1n Chain A

Receptor sequence
>6t1nA (length=141) Species: 9606 (Homo sapiens) [Search protein sequence]
QCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVF
WLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYD
LFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVM
3D structure
PDB6t1n Structural Insights into Interaction Mechanisms of Alternative Piperazine-urea YEATS Domain Binders in MLLT1.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 M7Z A F28 H56 S58 F59 P60 E75 S76 G77 Y78 A79 F81 F25 H53 S55 F56 P57 E72 S73 G74 Y75 A76 F78 PDBbind-CN: -logKd/Ki=5.46,Kd=3.5uM
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:6t1n, PDBe:6t1n, PDBj:6t1n
PDBsum6t1n
PubMed31857843
UniProtQ03111|ENL_HUMAN Protein ENL (Gene Name=MLLT1)

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