Structure of PDB 6t1j Chain A

Receptor sequence
>6t1jA (length=143) Species: 9606 (Homo sapiens) [Search protein sequence]
DNQCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKV
VFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFT
YDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVM
3D structure
PDB6t1j Structural Insights into Interaction Mechanisms of Alternative Piperazine-urea YEATS Domain Binders in MLLT1.
ChainA
Resolution1.97 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M7T A F28 H56 S58 F59 P60 G77 Y78 F27 H55 S57 F58 P59 G76 Y77 PDBbind-CN: -logKd/Ki=4.74,Kd=18.1uM
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:6t1j, PDBe:6t1j, PDBj:6t1j
PDBsum6t1j
PubMed31857843
UniProtQ03111|ENL_HUMAN Protein ENL (Gene Name=MLLT1)

[Back to BioLiP]