Structure of PDB 6t12 Chain A

Receptor sequence
>6t12A (length=160) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHSPIHWVLPMSAKMLGGVFKIDW
ICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDES
IDLYQVIHKM
3D structure
PDB6t12 Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
ChainA
Resolution1.46 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M78 A S378 L380 W428 M434 L439 S35 L37 W83 M87 L92 MOAD: ic50=825uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6t12, PDBe:6t12, PDBj:6t12
PDBsum6t12
PubMed32101404
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

[Back to BioLiP]