Structure of PDB 6t0z Chain A

Receptor sequence
>6t0zA (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKM
3D structure
PDB6t0z Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
ChainA
Resolution1.43 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M75 A K361 N367 S378 T379 L380 W428 M434 L439 D476 K18 N24 S35 T36 L37 W85 M91 L96 D133 MOAD: ic50>1000uM
Gene Ontology

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Molecular Function
External links
PDB RCSB:6t0z, PDBe:6t0z, PDBj:6t0z
PDBsum6t0z
PubMed32101404
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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