Structure of PDB 6t0x Chain A

Receptor sequence
>6t0xA (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKM
3D structure
PDB6t0x Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
ChainA
Resolution1.36 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M6W A K361 N367 W377 S378 W428 D476 K18 N24 W34 S35 W85 D133 MOAD: ic50>1000uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6t0x, PDBe:6t0x, PDBj:6t0x
PDBsum6t0x
PubMed32101404
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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