Structure of PDB 6t03 Chain A

Receptor sequence
>6t03A (length=161) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPSAKMLGGVFKID
WICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDE
SIDLYQVIHKM
3D structure
PDB6t03 Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MZY A W377 S378 W428 W34 S35 W85 MOAD: ic50>1000uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6t03, PDBe:6t03, PDBj:6t03
PDBsum6t03
PubMed32101404
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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