Structure of PDB 6szx Chain A

Receptor sequence
>6szxA (length=161) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHPIHWVLPAGMSAKMLGGVFKID
WICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDE
SIDLYQVIHKM
3D structure
PDB6szx Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
ChainA
Resolution1.17 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M4K A K361 N363 W377 S378 T379 W428 M434 D476 K18 N20 W34 S35 T36 W82 M88 D130 MOAD: Kd=58uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6szx, PDBe:6szx, PDBj:6szx
PDBsum6szx
PubMed32101404
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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