Structure of PDB 6sxc Chain A

Receptor sequence
>6sxcA (length=271) Species: 156889 (Magnetococcus marinus MC-1) [Search protein sequence]
SHMSRKIRDLIESKRFQNVITAIIVLNGAVLGLLTDTTLSASSQNLLERV
DQLCLTIFIVEISLKIYAYGVRGFFRSGWNLFDFVIVAIALMPAQGSLSV
LRTFRIFRVMRLVSVIPTMRRVVQGMLLALPGVGSVAALLTVVFYIAAVM
ATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVF
FIPFIMLTTLTVLNLFIGIIVDAMAITKEQEEEAKTGHHQEPISQTLLHL
GDRLDRIEKQLAQNNELLQRQ
3D structure
PDB6sxc A tamoxifen receptor within a voltage-gated sodium channel.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2CV A M189 P193 W196 M191 P195 W198
BS02 OHT A M222 A223 I241 M224 A225 I243
BS03 2CV A F172 M175 F174 M177
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005248 voltage-gated sodium channel activity
GO:0005261 monoatomic cation channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0001518 voltage-gated sodium channel complex
GO:0005886 plasma membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:6sxc, PDBe:6sxc, PDBj:6sxc
PDBsum6sxc
PubMed33503406
UniProtA0L5S6

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