Structure of PDB 6sqe Chain A

Receptor sequence
>6sqeA (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
KKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKN
PMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKL
AEVFEQEIDPVMQSLG
3D structure
PDB6sqe Crystal structure of CREBBP bromodomain complexed with KD341
ChainA
Resolution1.506 Å
3D
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LSZ A L1109 P1110 Q1113 V1115 L1120 N1168 R1173 V1174 L28 P29 Q32 V34 L39 N87 R92 V93
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6sqe, PDBe:6sqe, PDBj:6sqe
PDBsum6sqe
PubMed
UniProtQ92793|CBP_HUMAN CREB-binding protein (Gene Name=CREBBP)

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