Structure of PDB 6sq2 Chain A

Receptor sequence
>6sq2A (length=176) Species: 9606 (Homo sapiens) [Search protein sequence]
AKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIE
LDGKRIKLQIWDTAGLERFREITTAYYRGAMGIMLVYDITNEKSFDNIRN
WIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETS
AKANINVENAFFTLARDIKAKMDKKL
3D structure
PDB6sq2 Structure of a phosphomimetic switch 2 variant of Rab8a in complex with the phospho-Rab binding domain of RILPL2
ChainA
Resolution1.684 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP A S17 G18 V19 G20 K21 T22 C23 F33 S35 F37 T40 G66 K122 D124 S151 A152 K153 S16 G17 V18 G19 K20 T21 C22 F32 S34 F36 T39 G65 K121 D123 S150 A151 K152
BS02 MG A T22 T40 T21 T39
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:6sq2, PDBe:6sq2, PDBj:6sq2
PDBsum6sq2
PubMed
UniProtP61006|RAB8A_HUMAN Ras-related protein Rab-8A (Gene Name=RAB8A)

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