Structure of PDB 6spt Chain A

Receptor sequence
>6sptA (length=69) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
GAMWHTHSEREKRVSNAVEFLLDSRVRRTPTSSKVHFLKSKGLSAEEICE
AFTKVGQPKTLNEIKRILS
3D structure
PDB6spt Structure-Activity Relationship in Pyrazolo[4,3-c]pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction with Trypanocidal Activity.
ChainA
Resolution1.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FTW A N13 A14 E16 F17 R22 T26 F34 K38 N16 A17 E19 F20 R25 T29 F37 K41
Gene Ontology
Biological Process
GO:0016560 protein import into peroxisome matrix, docking
Cellular Component
GO:0005778 peroxisomal membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:6spt, PDBe:6spt, PDBj:6spt
PDBsum6spt
PubMed31860309
UniProtQ8IEW2

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