Structure of PDB 6sm1 Chain A

Receptor sequence
>6sm1A (length=111) Species: 9606 (Homo sapiens) [Search protein sequence]
SALTQPASVSGSPGQSITISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIY
EVSNRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCSSYTSSSTLYV
FGTGTKVTVLG
3D structure
PDB6sm1 Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E87 V112 G114 E84 V109 G111
Gene Ontology
Molecular Function
GO:0003823 antigen binding
Biological Process
GO:0002250 adaptive immune response
GO:0006955 immune response
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0019814 immunoglobulin complex
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6sm1, PDBe:6sm1, PDBj:6sm1
PDBsum6sm1
PubMed32151314
UniProtP01704|LV214_HUMAN Immunoglobulin lambda variable 2-14 (Gene Name=IGLV2-14)

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