Structure of PDB 6slo Chain A

Receptor sequence
>6sloA (length=214) Species: 1439318 (Citrobacter freundii MGH 56) [Search protein sequence]
PMSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADE
YQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQ
LKEFLDANLAGSAMESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNR
VIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAE
VYDQERFDNSDLSA
3D structure
PDB6slo Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly.
ChainA
Resolution1.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A I416 R417 G418 T421 I74 R75 G76 T79
BS02 MG A G418 V435 G76 V93
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0015035 protein-disulfide reductase activity

View graph for
Molecular Function
External links
PDB RCSB:6slo, PDBe:6slo, PDBj:6slo
PDBsum6slo
PubMed33159082
UniProtQ9UHX1|PUF60_HUMAN Poly(U)-binding-splicing factor PUF60 (Gene Name=PUF60)

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