Structure of PDB 6skq Chain A

Receptor sequence
>6skqA (length=245) Species: 562 (Escherichia coli) [Search protein sequence]
SITENMSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARASKEYLPASTFK
IPNAIIGLETGVIKNEHQVFKWDGKPRAMKQWERDLTLRGAIQVSALPVF
QQIAREVGEVRMQKYLKKFSYGNQNISGGIDKFWLEGQLRISAVNQVEFL
ESLYLNKLSASKENQLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVA
WWVGWVEKETEVYFFAFNMDIDNESKLPLRKSIPTKIMESEGIIG
3D structure
PDB6skq Structural insights into the enhanced carbapenemase efficiency of OXA-655 compared to OXA-10.
ChainA
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S67 K70 S115 F120 W154 F208
Catalytic site (residue number reindexed from 1) S47 K50 S95 F100 W134 F188
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MER A S67 W102 S115 L155 T206 G207 F208 R250 S47 W82 S95 L135 T186 G187 F188 R230
Gene Ontology
Molecular Function
GO:0008658 penicillin binding
GO:0008800 beta-lactamase activity
Biological Process
GO:0017001 antibiotic catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6skq, PDBe:6skq, PDBj:6skq
PDBsum6skq
PubMed32683794
UniProtA0A386YIZ1

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