Structure of PDB 6sk7 Chain A

Receptor sequence
>6sk7A (length=285) Species: 650130 (Human rhinovirus 89 ATCC VR-1199) [Search protein sequence]
NPVENYIDSVLNEVLVVPNIQPSTSVSSHAAPALDAAETGHTSSVQPEDM
IETRYVITDQTRDETSIESFLGRSGCIAMIEFNTSSDKTEHDKIGKGFKT
WKVSLQEMAQIRRKYELFTYTRFDSEITIVTAAAAQGNDSGHIVLQFMYV
PPGAPVPEKRDDYTWQSGTNASVFWQEGQPYPRFTIPFMSIASAYYMFYD
GYDGDSAASKYGSVVTNDMGTICVRIVTSNQKHDSNIVCRIYHKAKHIKA
WCPRPPRAVAYQHTHSTNYIPSNGEATTQIKTRPD
3D structure
PDB6sk7 Cryo-EM structure of pleconaril-resistant rhinovirus-B5 complexed to the antiviral OBR-5-340 reveals unexpected binding site.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D66 S69 E71 D127 K249 H250 D63 S66 E68 D124 K246 H247
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:6sk7, PDBe:6sk7, PDBj:6sk7
PDBsum6sk7
PubMed31462495
UniProtP07210|POLG_HRV8A Genome polyprotein

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