Structure of PDB 6sei Chain A

Receptor sequence
>6seiA (length=276) [Search protein sequence]
QCKPIPALYTVYVLRSTVRHASLYIGSTPNPPRRLKQHNGLVPGGAARTS
RSSLRPWEMVALVSGFPSMVAALKFQWALTNPHLSVHIPSASRRPQRPPR
SLASVVANLHLLLRVPSFARWPLRVHFFRRDVFAAWEKWCAAASERLRPS
LAVVTDFEGGSPCWGIHALPLDYEPIKDYVAKGQEIFEFERQGACVVCRE
EMASGDGLQALCTNQGCDGVGHLSCWSRHFLKEADSILPVQGQCPKCGGE
MEWGNMMKELTLRTRGQKEVEKLLKR
3D structure
PDB6sei Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease.
ChainA
Resolution2.69 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R22 H23 R51 R54 S56 R111 R19 H20 R48 R51 S53 R97
BS02 ZN A C229 C232 H256 C259 C195 C198 H222 C225
BS03 ZN A C246 C251 C280 C283 C212 C217 C244 C247
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0008821 crossover junction DNA endonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006281 DNA repair
GO:0006310 DNA recombination
Cellular Component
GO:0005634 nucleus
GO:0033557 Slx1-Slx4 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6sei, PDBe:6sei, PDBj:6sei
PDBsum6sei
PubMed31584081
UniProtG2QV68

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