Structure of PDB 6sdm Chain A

Receptor sequence
>6sdmA (length=354) Species: 29323 (Thermoanaerobacter brockii) [Search protein sequence]
HMMKGFAMLSIGKVGWIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGA
IGERHNMILGHEAVGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQRG
YHQHSGGMLAGWKFSNVKDGVFGEFFHVNDADMNLAHLPKEIPLEAAVMI
PDMMTTGFHGAELADIELGATVAVLGIGPVGLMAVAGAKLRGAGRIIAVS
KPPVCVDAAKYYGATDIVNVKDGPIESQIMNLTEGKGVDAAIIAGGNADI
MATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMAHKTIKGGLCPGG
RLRMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDKPKDLIKPV
VILA
3D structure
PDB6sdm Versatile selective evolutionary pressure using synthetic defect in universal metabolism.
ChainA
Resolution2.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C37 S39 H42 H59 D150
Catalytic site (residue number reindexed from 1) C39 S41 H44 H61 D152
Enzyme Commision number 1.1.1.80: isopropanol dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C37 S39 H59 C39 S41 H61
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0050009 isopropanol dehydrogenase (NADP+) activity

View graph for
Molecular Function
External links
PDB RCSB:6sdm, PDBe:6sdm, PDBj:6sdm
PDBsum6sdm
PubMed34824282
UniProtP14941|ADH_THEBR NADP-dependent isopropanol dehydrogenase (Gene Name=adh)

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