Structure of PDB 6scy Chain A

Receptor sequence
>6scyA (length=297) Species: 267377 (Methanococcus maripaludis S2) [Search protein sequence]
MITMKCRKCGKPSIYHQKHSGNNYCKECFIKETKRKVRKTLGRDVLKNNI
KVAMGLSGGKDSLVMAYLLNEYYKQIPNSNLIAIMVNEGIEGYRTDGIDA
AVKFCEEYGIEYKIVHFKDYLGTNLDEIVKLTMNPCSFCGVIRRKILNRV
SIEEKCDFLAIGHNLDDVAQAVMMNYIEGDVKKLAFLGKSLKHPKFVKRI
KPLEKIPEDEVLLLAEMLELKYHKSPCPYSCLSFRSEVSDITDNLEKNHP
GSKYSIVRGYERLLEHIELECKICGDLSATEVCKVCSYLKNLGILEK
3D structure
PDB6scy The thiolation of uridine 34 in tRNA, which controls protein translation, depends on a [4Fe-4S] cluster in the archaeum Methanococcus maripaludis.
ChainA
Resolution2.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C6 C9 C28 C6 C9 C28
BS02 SF4 A E88 R94 C142 C145 R149 C233 S236 E88 R94 C136 C139 R143 C227 S230
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0002098 tRNA wobble uridine modification
GO:0002143 tRNA wobble position uridine thiolation
GO:0008033 tRNA processing
GO:0034227 tRNA thio-modification
Cellular Component
GO:0002144 cytosolic tRNA wobble base thiouridylase complex

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Cellular Component
External links
PDB RCSB:6scy, PDBe:6scy, PDBj:6scy
PDBsum6scy
PubMed37005440
UniProtQ6LXJ4

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