Structure of PDB 6sch Chain A

Receptor sequence
>6schA (length=352) Species: 1520 (Clostridium beijerinckii) [Search protein sequence]
MKGFAMLGINKLGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALG
DRKNMILGHEAVGEVVEVGSEVKDFKPGDRVIVPCTTPDWRSLEVQAGFQ
QHSNGMLAGWKFSNFKDGVFGEYFHVNDADMNLAILPKDMPLENAVMITD
MMTTGFHGAELADIQMGSSVVVIGIGAVGLMGIAGAKLRGAGRIIGVDYR
PICVEAAKFYGATDILNPKNGHIVDQVMKLTNGKGVDRVIMAGGGSETLS
QAVSMVKPGGIISNINYHGSGDALLIPRVEWGCGMAHKTIKGGLCPGGRL
RAEMLRDMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKDKPKDLIKAVVI
LH
3D structure
PDB6sch Versatile selective evolutionary pressure using synthetic defect in universal metabolism.
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C37 S39 H42 H59 D150
Catalytic site (residue number reindexed from 1) C37 S39 H42 H59 D150
Enzyme Commision number 1.1.1.80: isopropanol dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A C37 T38 H42 H59 D150 G176 V178 D198 Y199 R200 A242 G244 N266 Y267 C37 T38 H42 H59 D150 G176 V178 D198 Y199 R200 A242 G244 N266 Y267
BS02 ZN A C37 H59 D150 C37 H59 D150
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0050009 isopropanol dehydrogenase (NADP+) activity

View graph for
Molecular Function
External links
PDB RCSB:6sch, PDBe:6sch, PDBj:6sch
PDBsum6sch
PubMed34824282
UniProtP25984|ADH_CLOBE NADP-dependent isopropanol dehydrogenase (Gene Name=adh)

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