Structure of PDB 6s84 Chain A

Receptor sequence
>6s84A (length=306) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
MRVLGIETSCDETAVAVLDDGKNVVVNFTVSRHHLKNLPILLKKAFEKVP
PETVDVVAATYGPGLIGALLVGLSAAKGLAISLEKPFVGVNHVEAHVQAV
FLANPDLKPPLVVLMVSGGHTQLMKVDEDYSMEVLGETLDDSAGEAFDKV
ARLLGLGYPGGPVIDRVAKKGDPEKYSFPRPMLDDDSYNFSFAGLKTSVL
YFLQREKGYKVEDVAASFQKAVVDILVEKTFRLARNLGIRKIAFVGGVAA
NSMLREEVRKRAERWNYEVFFPPTDNALMVAKAGYEKAKRGMFSPLSLNA
DPNLNV
3D structure
PDB6s84 The structure of the TsaB/TsaD/TsaE complex reveals an unexpected mechanism for the bacterial t6A tRNA-modification.
ChainA
Resolution2.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.234: N(6)-L-threonylcarbamoyladenine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 APC A S134 G135 H137 G161 D165 G178 P179 G264 V265 A267 N268 S117 G118 H120 G144 D148 G161 P162 G247 V248 A250 N251
BS02 APC A K166 G211 K213 K149 G194 K196
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0046872 metal ion binding
GO:0061711 N(6)-L-threonylcarbamoyladenine synthase activity
Biological Process
GO:0002949 tRNA threonylcarbamoyladenosine modification
GO:0008033 tRNA processing
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6s84, PDBe:6s84, PDBj:6s84
PDBsum6s84
PubMed29741707
UniProtQ9WXZ2|TSAD_THEMA tRNA N6-adenosine threonylcarbamoyltransferase (Gene Name=tsaD)

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