Structure of PDB 6s4g Chain A

Receptor sequence
>6s4gA (length=453) Species: 243365 (Chromobacterium violaceum ATCC 12472) [Search protein sequence]
TTSQWRELDAAHHLHPFTDTASLNQAGARVMTRGEGVYLWDSEGNKIIDG
MAGLWCVNVGYGRKDFAEAARRQMEELPFYNTFFKTTHPAVVELSSLLAE
VTPAGFDRVFYTNSGSESVDTMIRMVRRYWDVQGKPEKKTLIGRWNGYHG
STIGGASLGGMKYMHEQGDLPIPGMAHIEQPWWYKHGKDMTPDEFGVVAA
RWLEEKILEIGADKVAAFVGEPIQGAGGVIVPPATYWPEIERICRKYDVL
LVADEVICGFGRTGEWFGHQHFGFQPDLFTAAKGLSSGYLPIGAVFVGKR
VAEGLIAGGDFNHGFTYSGHPVCAAVAHANVAALRDEGIVQRVKDDIGPY
MQKRWRETFSRFEHVDDVRGVGMVQAFTLVKNKAKRELFPDFGEIGTLCR
DIFFRNNLIMRACGDHIVSAPPLVMTRAEVDEMLAVAERCLEEFEQTLKA
RGL
3D structure
PDB6s4g Insight into the dimer dissociation process of the Chromobacterium violaceum (S)-selective amine transaminase.
ChainA
Resolution1.67 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) F22 Y153 D259 K288
Catalytic site (residue number reindexed from 1) F17 Y148 D254 K283
Enzyme Commision number 2.6.1.62: adenosylmethionine--8-amino-7-oxononanoate transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PMP A S119 G120 S121 Y153 H154 G155 E226 D259 V261 I262 K288 S114 G115 S116 Y148 H149 G150 E221 D254 V256 I257 K283
BS02 PMP A F320 T321 F315 T316
Gene Ontology
Molecular Function
GO:0004015 adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
GO:0042802 identical protein binding
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6s4g, PDBe:6s4g, PDBj:6s4g
PDBsum6s4g
PubMed31740704
UniProtQ7NWG4

[Back to BioLiP]