Structure of PDB 6s0u Chain A

Receptor sequence
>6s0uA (length=276) Species: 1967 (Streptomyces kanamyceticus) [Search protein sequence]
ALAAPPGELTLALTPDDKTLDPASLDRALAILAEHGILVLTGMLRTRLTD
QLRTAMLDDLPEVLRQQDVPTNFVPGHVQQDPPVRESLLFPDVLLNPVVY
QITHAVLGADARNAVYSGNMNLPGSHEQPVHLDEPHLWPGISHPPYCLCV
DVPLIDFTLENGSTEYWPGSHVLNPDECYDERGCVLPAELERRRAVAPPV
RFPIPVGSVVIRDGRLWHRGVPNLSAAPRPLLAMTHYTEWFDMPPIQLPD
TVKSWVDGSDRHTHAHFVAGDVDHLT
3D structure
PDB6s0u A study on the structure, mechanism, and biochemistry of kanamycin B dioxygenase (KanJ)-an enzyme with a broad range of substrates.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.37: kanamycin B dioxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AKG A N73 N120 Q129 H132 T165 H219 G221 R230 N72 N119 Q128 H131 T164 H218 G220 R229
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
Biological Process
GO:0017000 antibiotic biosynthetic process
GO:1901133 kanamycin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6s0u, PDBe:6s0u, PDBj:6s0u
PDBsum6s0u
PubMed32592631
UniProtQ6L732|KANJ_STRKN Kanamycin B dioxygenase (Gene Name=kanJ)

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