Structure of PDB 6s0a Chain A

Receptor sequence
>6s0aA (length=208) Species: 9606 (Homo sapiens) [Search protein sequence]
SVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTH
ICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRK
FDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQ
RLCTPLLPKYPPTVSMVEKNVTFWGRPLPRCEELQGQKLVVEEKRPCLHV
PACKDPEE
3D structure
PDB6s0a Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b.
ChainA
Resolution2.52 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MAN A E323 W324 R368 W432 E69 W70 R114 W174
BS02 MAN A W321 R346 W67 R92
BS03 MAN A G259 W260 R282 A297 G5 W6 R28 A43
BS04 MAN A W263 R302 W9 R48
BS05 MAN A W382 E440 W128 E182
BS06 MAN A E384 W385 R403 R405 E130 W131 R149 R151
BS07 MAN A T387 W388 R401 T133 W134 R147
External links
PDB RCSB:6s0a, PDBe:6s0a, PDBj:6s0a
PDBsum6s0a
PubMed31552043
UniProtP27918|PROP_HUMAN Properdin (Gene Name=CFP)

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