Structure of PDB 6s08 Chain A

Receptor sequence
>6s08A (length=206) Species: 9606 (Homo sapiens) [Search protein sequence]
SVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTH
ICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRK
FDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQ
RLCTPLLPKYPPTVGEKNVTFWGRPLPRCEELQGQKLVVEEKRPCLHVPA
CKDPEE
3D structure
PDB6s08 Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b.
ChainA
Resolution2.03 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FUC A T272 C273 P313 T18 C19 P59
BS02 MAN A E323 W324 E69 W70
BS03 MAN A S320 W321 R346 S66 W67 R92
BS04 MAN A W382 E440 W128 E180
BS05 MAN A E384 W385 R403 E130 W131 R149
BS06 MAN A W260 R282 C296 A297 W6 R28 C42 A43
BS07 MAN A W263 R302 W9 R48
BS08 MAN A T387 W388 R401 T133 W134 R147
External links
PDB RCSB:6s08, PDBe:6s08, PDBj:6s08
PDBsum6s08
PubMed31552043
UniProtP27918|PROP_HUMAN Properdin (Gene Name=CFP)

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