Structure of PDB 6ryo Chain A

Receptor sequence
>6ryoA (length=155) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
HMHKKYFIGTSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITS
HRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNLFMQVAISLL
FAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIA
LLKDT
3D structure
PDB6ryo Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin.
ChainA
Resolution1.924 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.23.36: signal peptidase II.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A N52 W57 F67 T71 A103 N106 R110 V116 D118 D136 N53 W58 F68 T72 A104 N107 R111 V117 D119 D137
BS02 ZN A H0 H2 H1 H3
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ryo, PDBe:6ryo, PDBj:6ryo
PDBsum6ryo
PubMed31919415
UniProtQ6GHN9|LSPA_STAAR Lipoprotein signal peptidase (Gene Name=lspA)

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