Structure of PDB 6rxs Chain A

Receptor sequence
>6rxsA (length=218) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
KPRVLVLTGAGISAESGIRTFRARDPELVQAFANARRRQLQQPEIQPNAA
HLALAKLQDALGDRFLLVTQNLDNLHERAGNTNVIHMHGELLKVRCSQSG
QVLDWTGDVTPEDKCHCCQFPAPLRPHYVWFGEMPLGMDEIYMALSMADI
FIAIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQVGNEFAEKYYGPAS
QVVPEFVEKLLKGLKAGS
3D structure
PDB6rxs Evolved, Selective Erasers of Distinct Lysine Acylations.
ChainA
Resolution1.599 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.286: protein acetyllysine N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H147 V188 F190 G191 E192 M193 P194 Y201 H218 V219 Y220 E228 Q245 H88 V129 F131 G132 E133 M134 P135 Y142 H159 V160 Y161 E169 Q186
BS02 ZN A C155 C174 C177 C96 C115 C118
Gene Ontology
Molecular Function
GO:0036054 protein-malonyllysine demalonylase activity
GO:0036055 protein-succinyllysine desuccinylase activity
GO:0070403 NAD+ binding

View graph for
Molecular Function
External links
PDB RCSB:6rxs, PDBe:6rxs, PDBj:6rxs
PDBsum6rxs
PubMed32187803
UniProtP75960|NPD_ECOLI NAD-dependent protein deacylase (Gene Name=cobB)

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