Structure of PDB 6rvz Chain A

Receptor sequence
>6rvzA (length=346) Species: 9606 (Homo sapiens) [Search protein sequence]
GVIKRNWEYINKFDFSVMSYNILSQDLLEDNSHLYRHCRRPVLHWSFRFP
NILKEIKHFDADVLCLQEVQEDHYGAEIRPSLESLGYHCEYKMRTGRKPD
GCAICFKHSKFSLLSVNPVEFFRPDISLLDRDNVGLVLLLQPKIPCPAIC
VANTHLLYNPRRGDIKLTQLAMLLAEISSVAHQKDGSFCPIVMCGDFNSV
PGSPLYSFIKEGKLNYEGLPIGKVSGQEQSSRGQRILSIPIWPPNLGISQ
NCVYEVQQVPSSNLQHHFSLSSVYSHYFPDTGIPEVTTCHSRSAITVDYI
FYSAGLKLLARLSLLTEQDLWTVNGLPNENNSSDHLPLLAKFRLEL
3D structure
PDB6rvz ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KL2 A N173 L179 N183 L186 E220 H310 Y313 D351 N353 H533 N21 L27 N31 L34 E68 H155 Y158 D196 N198 H335
BS02 ADN A S472 W519 S291 W321
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:6rvz, PDBe:6rvz, PDBj:6rvz
PDBsum6rvz
PubMed32732418
UniProtQ5VTE6|ANGE2_HUMAN Protein angel homolog 2 (Gene Name=ANGEL2)

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