Structure of PDB 6rus Chain A

Receptor sequence
>6rusA (length=234) Species: 9606 (Homo sapiens) [Search protein sequence]
DPVLCFTQYEESSGKCKGLLGGGVSVEDCCLNTAFAYQKRSGGLCQPCRS
PRWSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQAC
EDQQCCPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQ
AQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAP
EPSQKPPGKPCPGLAYEQRRCTGLPPCPENLYFQ
3D structure
PDB6rus Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BGC A V150 H193 V123 H166
BS02 BGC A C209 P255 N257 C182 P228 N230
BS03 MAN A L82 W83 L55 W56
BS04 MAN A T85 W86 T58 W59
BS05 MAN A G138 W139 R161 G111 W112 R134
BS06 MAN A W142 R159 W115 R132
BS07 MAN A P144 W145 R157 P117 W118 R130
BS08 MAN A A195 W196 R222 A168 W169 R195
BS09 MAN A W199 R220 W172 R193
BS10 MAN A P201 W202 P174 W175
External links
PDB RCSB:6rus, PDBe:6rus, PDBj:6rus
PDBsum6rus
PubMed31507604
UniProtP27918|PROP_HUMAN Properdin (Gene Name=CFP)

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