Structure of PDB 6rsj Chain A

Receptor sequence

>6rsjA (length=108) Species: 559292 (Saccharomyces cerevisiae S288C)

AEFKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSGQAEG
YSYTDANIKKNVLWDENNMSEYLTNPKKYIPGTKMAFGGLKKEKDRNDLI
TYLKKATE

3D structure

• PDB: 6rsj Tuning Protein Frameworks via Auxiliary Supramolecular Interactions.
• Chain: A
• Resolution: 2.27 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEC	A	R13 C14 C17 H18 V28 P30 I35 S40 G41 Y48 T49 N52 W59 M64 Y67 L68 T78 M80 A81 F82	R18 C19 C22 H23 V33 P35 I40 S45 G46 Y53 T54 N57 W64 M69 Y72 L73 T83 M85 A86 F87
BS02	EVB	A	K11 L15 Q16 T19 P25 K27	K16 L20 Q21 T24 P30 K32
BS03	EVB	A	A-1 A3 K4 T96 Y97 K100	A5 A8 K9 T101 Y102 K105
BS04	EVB	A	R13 N70 K72 K73 A81 F82 G83 G84 K86	R18 N75 K77 K78 A86 F87 G88 G89 K91

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0009055 electron transfer activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:1901612 cardiolipin binding

Biological Process

• GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
• GO:0006123 mitochondrial electron transport, cytochrome c to oxygen

Cellular Component

• GO:0005739 mitochondrion
• GO:0005758 mitochondrial intermembrane space

External links

• PDB: RCSB:6rsj, PDBe:6rsj, PDBj:6rsj
• PDBsum: 6rsj
• PubMed: 31490058
• UniProt: P00044|CYC1_YEAST Cytochrome c isoform 1 (Gene Name=CYC1)