Structure of PDB 6rrp Chain A

Receptor sequence
>6rrpA (length=459) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
PQTPDEASLDLAATDGIRLGDRLRGLWDLRLVGGDAELPGLPREGLQLVL
DVAPKGRGLIGYLDTPERLLAAEPPRFRVLGDLLGASSASIRWRLVDQAS
GSVAPTHDCSAVFDEVWGDGTLSGRIQRLERSNEDFRFVAVKRHFPLAHE
RIVLNEKLLGWLVSPQHRLFHQLWHASRDKWHRLSEKQRNALRGVGWQPG
PLDRERDARGPRKDRNASGIDFFFMHRHMLHTARSMQDLPSWERLPRPVV
PLEYDRPGFIRYFDNPDGFSVPPAWVAVDDDEYSEWLHGLKSAEAYHANF
LVWESQYQDPAYLAKLTLGQFGSELELGMHDWLHMRWASVTTDRFPADFA
PRWFRPENDFLGDPFSSHVNPVFWSFHGWIDDRIEDWYRAHERFHPGEVQ
RREVEGIQWFAPGRWVEVGDPWLGPATHGCGLELDVETMKLALRIIFSRP
WYARNLKLA
3D structure
PDB6rrp A novel mechanism of inhibition by phenylthiourea on PvdP, a tyrosinase synthesizing pyoverdine of Pseudomonas aeruginosa.
ChainA
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 URS A R53 W320 S329 E330 H333 R18 W275 S284 E285 H288 MOAD: ic50=174.4uM
BS02 CU A H216 H220 H271 H171 H175 H226
BS03 CU A H375 H379 H432 H330 H334 H377
Gene Ontology
Molecular Function
GO:0004503 tyrosinase activity
GO:0046872 metal ion binding
Biological Process
GO:0002049 pyoverdine biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6rrp, PDBe:6rrp, PDBj:6rrp
PDBsum6rrp
PubMed31899238
UniProtQ9I188

[Back to BioLiP]