Structure of PDB 6rgc Chain A

Receptor sequence
>6rgcA (length=259) Species: 169963 (Listeria monocytogenes EGD-e) [Search protein sequence]
MKYMITSKGDEKSDLLRLNMIAGFGEYDMEYDDVEPEIVISIGGDGTFLS
AFHQYEERLDEIAFIGIHTGHLGFYADWRPAEADKLVKLLAKGEYQKVSY
PLLKTTVKYEATYLALNESTVKSSGGPFVVDVVINDIHFERFRGDGLCMS
TPSGTTAYNKSLGGALMHPSIEAMQLTEMASINNRVYRTIGSPLVFPKHH
VVSLQPVNDKDFQISVDHLSILHRDVQEIRYEVSAKKIHFARFRSFPFWR
RVHDSFIED
3D structure
PDB6rgc From Substrate to Fragments to Inhibitor ActiveIn VivoagainstStaphylococcus aureus.
ChainA
Resolution2.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.23: NAD(+) kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 K3H A D45 G46 L72 F74 N122 E123 T161 A162 Y163 S166 D45 G46 L72 F74 N117 E118 T156 A157 Y158 S161
Gene Ontology
Molecular Function
GO:0003951 NAD+ kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0046872 metal ion binding
GO:0051287 NAD binding
Biological Process
GO:0006741 NADP biosynthetic process
GO:0016310 phosphorylation
GO:0019674 NAD metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6rgc, PDBe:6rgc, PDBj:6rgc
PDBsum6rgc
PubMed32017533
UniProtQ8Y8D7|NADK1_LISMO NAD kinase 1 (Gene Name=nadK1)

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