Structure of PDB 6rfz Chain A

Receptor sequence

>6rfzA (length=340) Species: 243265 (Photorhabdus laumondii subsp. laumondii TTO1) [Search protein sequence]

IALSEIVSVVNTSDGRIEVFGVGTDNAVWHNRQTAPHSGSSWTGWISLNG
KVTSKPVVYINTDGRLEVFARGTDNALWHIWQTATNAGWSNWQSLGGTIT
SNPAVYVNTDGRIDVFARGTDNALWHISQTAAHSGPWSSWQSLNGVITSN
PAVHINSDGRLEVFARGTDNALWHIWQTAPDSNQWSGWDSLGGVITSDPV
VIGTADGRLEVFARGSNNALYHIWQTVPHGGPWSNWASLNGVITSAPAVV
KNSDGRLEVFARGTNNALYHIWQTVSHSGPWSNWATLNGTITSAPTAVED
ADGRLEVFARGTDNALWNIWQAWSAWVSLKGSLIDASAIK

3D structure

PDB

6rfz Heptabladed beta-propeller lectins PLL2 and PHL from Photorhabdus spp. recognize O-methylated sugars and influence the host immune system.

Chain

Resolution

1.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	BGC	A	R93 E95 H107 W109 W165	R65 E67 H79 W81 W137	MOAD: Kd=3.56mM
BS02	BGC	A	R188 E190 H202 W204 W261	R160 E162 H174 W176 W233	MOAD: Kd=3.56mM
BS03	BGC	A	R236 E238 H250 W252 Q301 W309	R208 E210 H222 W224 Q273 W281	MOAD: Kd=3.56mM
BS04	BGC	A	R284 E286 H298 W300 Q349 W354	R256 E258 H270 W272 Q321 W323	MOAD: Kd=3.56mM

External links

PDB	RCSB:6rfz, PDBe:6rfz, PDBj:6rfz
PDBsum	6rfz
PubMed	32559333
UniProt	Q7N8I8

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