Structure of PDB 6rcn Chain A

Receptor sequence
>6rcnA (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
GAMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLNILAEGPNLIIKQP
DELLDSMSDWCKEHHGKSGLTKAVKESTITLQQAEYEFLSFVRQQTPPGL
CPLAGNSVHEDKKFLDKYMPQFMKHLHYRIIDVSTVKELCRRWYPEEYEF
APKKAASHRALDAISESIKELQFYRNNIFK
3D structure
PDB6rcn Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.15.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A E49 M50 L53 W96 C97 H101 N142 S143 S170 H194 E13 M14 L17 W60 C61 H65 N106 S107 S134 H158
BS02 ZN A E49 H194 E13 H158
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:6rcn, PDBe:6rcn, PDBj:6rcn
PDBsum6rcn
PubMed31588022
UniProtQ9Y3B8|ORN_HUMAN Oligoribonuclease, mitochondrial (Gene Name=REXO2)

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