Structure of PDB 6r7s Chain A

Receptor sequence

>6r7sA (length=567) Species: 9606 (Homo sapiens) [Search protein sequence]

SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCV
ADESAENCDKSLHTLFGDKLCTDCCAKQEPERNECFLQHKDDNPNLPRLV
RPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFT
ECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAV
ARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICE
NQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVC
KNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADP
HECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVP
QVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEK
TPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTL
SEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKET
CFAEEGKKLVAASQAAL

3D structure

PDB

6r7s Resolving Binding Events on the Multifunctional Human Serum Albumin.

Chain

Resolution

2.21 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	SAS	A	L198 K199 S202 F211 W214 R218 L238 S287 I290 A291	L182 K183 S186 F195 W198 R202 L222 S271 I274 A275
BS02	SAS	A	L394 N405 V409 R410 K541 L544 K545 M548	L378 N389 V393 R394 K525 L528 K529 M532
BS03	SAS	A	T506 F507 T508 K524 K525 T527 A528 E531 F551 A552 V555	T490 F491 T492 K508 K509 T511 A512 E515 F535 A536 V539

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0005504	fatty acid binding
GO:0005507	copper ion binding
GO:0005515	protein binding
GO:0008289	lipid binding
GO:0015643	toxic substance binding
GO:0016209	antioxidant activity
GO:0019825	oxygen binding
GO:0030170	pyridoxal phosphate binding
GO:0042802	identical protein binding
GO:0046872	metal ion binding
GO:0051087	protein-folding chaperone binding
GO:0140272	exogenous protein binding
GO:1903981	enterobactin binding

	Biological Process
GO:0009267	cellular response to starvation
GO:0051902	negative regulation of mitochondrial depolarization
GO:0072732	cellular response to calcium ion starvation
GO:0098869	cellular oxidant detoxification

	Cellular Component
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005788	endoplasmic reticulum lumen
GO:0005794	Golgi apparatus
GO:0031093	platelet alpha granule lumen
GO:0032991	protein-containing complex
GO:0070062	extracellular exosome
GO:0072562	blood microparticle

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6r7s, PDBe:6r7s, PDBj:6r7s
PDBsum	6r7s
PubMed	32162429
UniProt	P02768\|ALBU_HUMAN Albumin (Gene Name=ALB)

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