Structure of PDB 6r64 Chain A

Receptor sequence
>6r64A (length=145) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
EFMHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYII
ERLVDSGVSQVVVYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRL
KMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRG
3D structure
PDB6r64 Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
ChainA
Resolution2.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A S30 G32 P33 S65 S66 S108 R109 K113 G118 N119 K122 S32 G34 P35 S67 S68 S110 R111 K115 G120 N121 K124 PDBbind-CN: Kd=2.2nM
BS02 dna A W31 P33 R97 L98 R120 W33 P35 R99 L100 R122 PDBbind-CN: Kd=2.2nM
External links
PDB RCSB:6r64, PDBe:6r64, PDBj:6r64
PDBsum6r64
PubMed31724709
UniProtP24200|MCRA_ECOLI Type IV methyl-directed restriction enzyme EcoKMcrA (Gene Name=mcrA)

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