Structure of PDB 6r5g Chain A

Receptor sequence
>6r5gA (length=119) Species: 9606 (Homo sapiens) [Search protein sequence]
GPMADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSV
RTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNP
MVETLGTVLQLKQPLNTTR
3D structure
PDB6r5g Molecular mechanism of SHP2 activation by PD-1 stimulation.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R138 S140 Q141 S142 V148 K166 T168 H169 V170 M171 V181 G182 G183 M202 V203 E204 T205 T208 R37 S39 Q40 S41 V47 K65 T67 H68 V69 M70 V80 G81 G82 M101 V102 E103 T104 T107
External links
PDB RCSB:6r5g, PDBe:6r5g, PDBj:6r5g
PDBsum6r5g
PubMed32064351
UniProtQ06124|PTN11_HUMAN Tyrosine-protein phosphatase non-receptor type 11 (Gene Name=PTPN11)

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